Puromycin
Puromycin dihydrochloride is an aminonucleoside antibiotic that causes premature chain termination by mimicking aminoacyl-tRNA. In research, it is the standard selectable marker in lentiviral and retroviral vector systems expressing the puromycin N-acetyltransferase (pac) resistance gene. Provides rapid selection (~2-5 days); essential tool for stable cell line generation.
Description
Scientific Overview: Puromycin dihydrochloride is an aminonucleoside antibiotic that causes premature chain termination by mimicking aminoacyl-tRNA. In research, it is the standard selectable marker in lentiviral and retroviral vector systems expressing the puromycin N-acetyltransferase (pac) resistance gene. Provides rapid selection (~2-5 days); essential tool for stable cell line generation.
Mechanism of Action: Protein Synthesis Inhibitor (aminonucleoside antibiotic)
Purity: ≥99% | Molecular Formula: C22H29N7O5 · 2HCl
For Research Use Only. Not intended for diagnostic, therapeutic, or clinical applications.
Additional information
| Effect | Protein Synthesis Inhibitor (aminonucleoside antibiotic) |
|---|---|
| Purity | ≥99% |
| Molecular Formula | C22H29N7O5 · 2HCl |
| CAS Number | 58-58-2 |
